Jun Morinaga Selected Research

Angiopoietin-Like Protein 2

9/2021	Serum Angiopoietin-Like Protein 2 and NT-Pro BNP Levels and Their Associated Factors in Patients with Chronic Heart Failure Participating in a Phase III Cardiac Rehabilitation Program.
1/2021	Stroma-derived ANGPTL2 establishes an anti-tumor microenvironment during intestinal tumorigenesis.
4/2020	Tumor cell-derived angiopoietin-like protein 2 establishes a preference for glycolytic metabolism in lung cancer cells.
1/2019	Angiopoietin-Like Protein 2 Promotes the Progression of Diabetic Kidney Disease.
1/2018	Circulating ANGPTL2 Levels Increase in Humans and Mice Exhibiting Cardiac Dysfunction.
1/2017	ANGPTL2 expression in the intestinal stem cell niche controls epithelial regeneration and homeostasis.
2/2016	Angiopoietin-like protein 2 increases renal fibrosis by accelerating transforming growth factor-β signaling in chronic kidney disease.
1/2016	Macrophage-Derived Angiopoietin-Like Protein 2 Exacerbates Brain Damage by Accelerating Acute Inflammation after Ischemia-Reperfusion.
1/2016	Mice Deficient in Angiopoietin-like Protein 2 (Angptl2) Gene Show Increased Susceptibility to Bacterial Infection Due to Attenuated Macrophage Activity.
3/2015	ANGPTL2 increases bone metastasis of breast cancer cells through enhancing CXCR4 signaling.

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Jun Morinaga Research Topics

Disease

8	Neoplasms (Cancer) 01/2022 - 03/2015
7	Inflammation (Inflammations) 01/2022 - 01/2016
7	Fibrosis (Cirrhosis) 10/2016 - 10/2012
4	Heart Failure 09/2021 - 01/2018
3	Proteinuria 08/2021 - 10/2012
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 01/2018
3	Chronic Renal Insufficiency 02/2016 - 01/2015
2	Neoplasm Metastasis (Metastasis) 12/2021 - 01/2018
2	Lung Neoplasms (Lung Cancer) 12/2021 - 04/2020
2	Obesity 11/2021 - 01/2016
2	Atherosclerosis 11/2021 - 01/2016
2	Hypertension (High Blood Pressure) 08/2021 - 10/2012
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 08/2021 - 01/2016
2	Wounds and Injuries (Trauma) 08/2021 - 10/2016
2	Hypertrophy 01/2019 - 10/2012
2	Ureteral Obstruction 10/2016 - 07/2013
1	Cholangiocarcinoma 01/2022
1	Carcinogenesis 01/2022
1	Colorectal Neoplasms (Colorectal Cancer) 01/2022
1	Intestinal Neoplasms (Intestinal Cancer) 01/2022
1	Hyperglycemia 12/2021
1	Thrombocytopenia (Thrombopenia) 12/2021
1	Myocardial Infarction 12/2021
1	Cardiogenic Shock 12/2021
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2021
1	Fatty Liver 11/2021
1	Dyslipidemias (Dyslipidemia) 11/2021
1	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 11/2021
1	Adenoma (Adenomas) 11/2021
1	Body Weight (Weight, Body) 09/2021
1	Rodent Diseases 08/2021
1	Extramammary Paget Disease (Paget Disease, Extramammary) 02/2021
1	Surgical Wound Infection 06/2020
1	Premature Aging 01/2020
1	Melanoma (Melanoma, Malignant) 01/2020
1	Renal Cell Carcinoma (Grawitz Tumor) 06/2019
1	Kidney Neoplasms (Kidney Cancer) 06/2019
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2019
1	Osteosarcoma (Osteogenic Sarcoma) 01/2018
1	Muscular Atrophy (Muscle Atrophy) 01/2018
1	Hypoxia (Hypoxemia) 01/2018
1	Metabolic Diseases (Metabolic Disease) 01/2018

Drug/Important Bio-Agent (IBA)

10	Angiopoietin-Like Protein 2IBA 09/2021 - 03/2015
7	Proteins (Proteins, Gene)FDA Link 09/2021 - 10/2012
7	Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA 08/2021 - 10/2012
5	camostatIBA 08/2021 - 07/2013
3	CreatinineIBA 01/2022 - 10/2012
3	Angiopoietin-like ProteinsIBA 01/2022 - 01/2016
3	Serine Proteases (Serine Protease)IBA 08/2021 - 03/2014
2	Triglycerides (Triacylglycerol)IBA 01/2022 - 11/2021
2	C-Reactive ProteinIBA 01/2022 - 09/2021
2	MicroRNAs (MicroRNA)IBA 01/2020 - 06/2019
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 06/2019
2	SaltsIBA 10/2016 - 10/2012
2	Adenine FDA LinkGeneric 02/2016 - 01/2015
2	Transforming Growth Factors (Transforming Growth Factor)IBA 02/2016 - 07/2013
2	CytokinesIBA 01/2016 - 01/2016
2	CollagenIBA 07/2013 - 10/2012
1	osteoblast cadherinIBA 01/2022
1	CateninsIBA 01/2022
1	Gemcitabine FDA Link 01/2022
1	Uric Acid (Urate)IBA 01/2022
1	Cisplatin (Platino)FDA LinkGeneric 01/2022
1	Fluorouracil (Carac)FDA LinkGeneric 01/2022
1	Blood Glucose (Blood Sugar)IBA 12/2021
1	osimertinibIBA 12/2021
1	LigandsIBA 12/2021
1	ErbB Receptors (EGF Receptor)IBA 12/2021
1	Apolipoproteins E (ApoE)IBA 11/2021
1	Angiopoietin-Like Protein 3IBA 11/2021
1	LDL CholesterolIBA 11/2021
1	Protein Subunit VaccinesIBA 11/2021
1	EpitopesIBA 11/2021
1	VaccinesIBA 11/2021
1	oxidized low density lipoproteinIBA 11/2021
1	Peptides (Polypeptides)IBA 11/2021
1	CholesterolIBA 11/2021
1	LipidsIBA 11/2021
1	pro-brain natriuretic peptide (1-76)IBA 09/2021
1	Brain Natriuretic Peptide (Natrecor)FDA Link 09/2021
1	ParaffinIBA 02/2021
1	Interleukin-17 (Interleukin 17)IBA 02/2021
1	AdiponectinIBA 01/2021
1	CarcinogensIBA 01/2021
1	Long Noncoding RNAIBA 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2021
1	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 04/2020
1	HMGB2 ProteinIBA 01/2019
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 01/2018
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2018
1	Monoclonal AntibodiesIBA 01/2018
1	Interleukin-6 (Interleukin 6)IBA 01/2018

Therapy/Procedure

6	Therapeutics 01/2022 - 02/2016
1	Drug Therapy (Chemotherapy) 01/2022
1	Extracorporeal Membrane Oxygenation 12/2021
1	Cardiac Rehabilitation 09/2021
1	Antibiotic Prophylaxis 06/2020
1	Renal Dialysis (Hemodialysis) 01/2020
1	Denervation 01/2018
1	Resistance Training 01/2018